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45,590 documents matched Heterozygote
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A method for genotype validation and primer assessment in heterozygote-deficient species, as demonstrated in the prosobranch mollusc Hydrobia ulvae.screening for unreliable markers often relies on the identification of heterozygote deficiencies and subsequent departures from HWE. However, since many ...
BMC Genet, January 2008
 
 
Major histocompatibility complex (MHC) heterozygote superiority to natural multi-parasite infections in the water vole (Arvicola terrestris).is unclear. Two hypotheses have been proposed: overdominance (or heterozygote superiority) and negative frequency-dependent selection. Evidence for ...
Proc Biol Sci, March 2009
 
 
Inbreeding depression and multiple regions showing heterozygote advantage in Drosophila melanogaster exposed to stress.is widespread or an evolutionary oddity. We therefore quantified heterozygote advantage at 12 microsatellite markers in both inbred and outbred ...
Mol Ecol, November 2006
 
 
Histological skin changes in heterozygote carriers of mutations in ABCC6, the gene causing pseudoxanthoma elasticum.pathologically by dystrophic and mineralized elastic fibres. Heterozygote carriers of ABCC6 mutations may have a limited PXE phenotype. ...
J Eur Acad Dermatol Venereol, March 2007
 
 
An asymmetric model of heterozygote advantage at major histocompatibility complex genes: degenerate pathogen recognition and intersection advantage.as well as the degree of recognition degeneracy, m, into a model of heterozygote advantage that utilizes a set-theoretic definition of fitness. ...
Genetics, March 2008
 
 
NA1/NA2 heterozygote of Fcgr3b is a risk factor for progression of IgA nephropathy in Chinese.of the disease onset. We found that the genotype frequency of Fcgr3b heterozygote NA1/NA2 in IgAN patients in Chinese significantly higher than that of ...
J Clin Lab Anal, January 2007
 
 
NA1/NA2 heterozygote of Fcgr3b is a risk factor for progression of IgA nephropathy in Chinese.of the disease onset. We found that the genotype frequency of Fcgr3b heterozygote NA1/NA2 in IgAN patients in Chinese significantly higher than that of ...
J Clin Lab Anal, January 2007
 
 
NA1/NA2 heterozygote of Fcgr3b is a risk factor for progression of IgA nephropathy in Chinese.of the disease onset. We found that the genotype frequency of Fcgr3b heterozygote NA1/NA2 in IgAN patients in Chinese significantly higher than that of ...
J Clin Lab Anal, January 2007
 
 
Correlation between clinical phenotypes and X-inactivation patterns in six female carriers with heterozygote vasopressin type 2 receptor gene mutations.We studied X-inactivation patterns of six female carriers with heterozygote V2R gene mutations. The X-inactivation pattern in peripheral blood ...
Endocr J, May 2008
 
 
Self-fertilization in mosses: a comparison of heterozygote deficiency between species with combined versus separate sexes.dioicous mosses, monoicous species had significantly higher levels of heterozygote deficiency than dioicous species (F(IS)=0.89+/-0.12 and 0.41+/-0.11, ...
Heredity, January 2007
 
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